Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1547

MIN ACTIVATION

0.0

Details List

#2101 Feature #2101

#2105 Feature 2105

#886 Feature #886

#1092 Feature 1092

#1526 Feature #1526

#2216 Feature 2216

#2085 Feature #2085

#286 Feature #286

#2178 Feature #2178

#2392 Feature 2392

#498 Feature 498

#2678 Feature 2678

#1693 Feature 1693

#1971 Feature #1971

#1843 Feature 1843

#2874 Feature #2874

#167 Feature 167

#1494 Feature #1494

#575 Feature 575

#1192 Feature #1192

#1573 Feature 1573

#29 Feature #29

#1009 Feature 1009

#2997 Feature #2997

#1180 Feature 1180

#500 Feature #500

#2740 Feature 2740

#189 Feature 189

#909 Feature 909

#2358 Feature 2358

#558 Feature #558

#1099 Feature #1099

#534 Feature #534

#2821 Feature 2821

#1302 Sensing and Detection Technologies

#3069 Feature #3069

#2691 Feature 2691

#2593 Feature 2593

#1756 Feature #1756

#2766 Feature #2766

#2819 Feature 2819

#316 Feature #316

#2397 Feature 2397

#1793 Feature 1793

#830 Feature 830

#2081 Feature #2081

#2033 Feature 2033

#1375 Feature 1375

#584 Feature #584

#2247 Feature #2247

#554 Feature 554

#404 Interactions and Mechanisms

#806 Feature #806

#698 Feature #698

#1691 Feature #1691

#2025 Feature #2025

#1896 Feature 1896

#2382 Feature #2382

#728 Feature #728

#2973 Feature #2973

#1914 Feature 1914

#1113 Feature 1113

#425 Feature 425

#872 Feature #872

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#715 Feature #715

#314 Feature 314

#1781 Feature 1781

#2511 Feature #2511

#1572 Feature 1572

#3027 Feature 3027

#1233 Feature 1233

#1652 Feature #1652

#3055 Feature 3055

#1895 Feature 1895

#2094 Feature 2094

#224 Feature #224

#2626 Feature 2626

#609 Feature 609

#1397 Feature #1397

#113 Feature #113

#1159 Feature 1159

#1794 Feature 1794

#677 Feature 677

#1091 Feature #1091

#939 Feature 939

#2747 Feature 2747

#1501 Feature 1501

#1107 Feature 1107

#2862 Feature 2862

#2992 Feature #2992

#2447 Feature 2447

#2516 Feature 2516

#497 Feature #497

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#900 Feature 900

#1690 Feature 1690

#2380 Feature 2380

#436 Feature 436

#1565 Feature #1565

#740 Feature #740

#3066 Feature 3066

#1015 Feature 1015

#1412 Feature #1412

#2069 Feature 2069

#2600 Feature #2600

#1731 Feature 1731

#1448 Feature #1448

#302 Feature 302

#2713 Feature #2713

#178 Feature 178

#211 Feature 211

#1078 Feature #1078

#2117 Feature 2117

#2370 Feature 2370

#1842 Feature #1842

#681 Feature #681

#2241 Feature #2241

#2495 Feature 2495

#563 Feature 563

#463 Feature #463

#1795 Feature 1795

#169 Feature 169

#913 Feature #913

#1860 Feature 1860

#2121 Feature #2121

#653 Feature 653

#2222 Feature 2222

#1027 Feature 1027

#351 Nanomaterial Synthesis and Properties

#1285 Feature 1285

#451 Feature #451

#1343 Feature #1343

#2514 Feature #2514

#2983 Feature #2983

#960 Feature #960

#450 Feature 450

#1549 Feature #1549

#600 Feature 600

#778 Feature 778

#1505 Feature #1505

#1355 Feature 1355

#836 Feature #836

#916 Feature #916

#2204 Feature #2204

#2530 Feature 2530

#2242 Feature 2242

#405 Feature #405

#1290 Feature 1290

#945 Feature 945

#555 Feature 555

#1394 Feature 1394

#373 Feature #373

#1727 Feature #1727

#1379 Feature 1379

#2533 Feature 2533

#1034 Feature 1034

#578 Feature #578

#2022 Feature 2022

#2575 Feature 2575

#394 Feature #394

#2017 Feature #2017

#2982 Feature 2982

#1283 Feature 1283

#894 Feature #894

#2102 Feature #2102

#2555 Feature 2555

#2232 Medical Case Reports & Cancer Research

#2186 Feature #2186

#2391 Feature #2391

#2893 Feature 2893

#2566 Feature #2566

#150 Feature 150

#2250 Feature 2250

#2646 Feature #2646

#1406 Feature #1406

#902 Feature #902

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#1774 Feature 1774

#1346 Feature 1346

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#75 Feature #75

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#2637 Feature #2637

#2739 Feature #2739

#588 Feature 588

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#403 Feature #403

#2867 Feature #2867

#488 Feature 488

#1030 Feature 1030

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#509 Feature #509

#2066 Feature #2066

#380 Feature 380

#3006 Feature #3006

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#2901 Feature 2901

#1951 Feature 1951

#974 Feature 974

#2225 Feature 2225

#136 Feature #136

#2728 Feature 2728

#2319 Feature 2319

#1683 Feature #1683

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#2561 Feature #2561

#2164 Feature #2164

#1889 Feature #1889

#870 Feature 870

#2597 Feature #2597

#1184 Feature #1184

#1496 Feature #1496

#1782 Feature #1782

#2240 Feature #2240

#708 Drug Resistance Mechanisms in Cancer

#2732 Feature 2732

#2505 Feature #2505

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#1147 Feature #1147

#1834 Feature 1834

#1666 Feature 1666

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#106 Feature #106

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#529 Feature #529

#2387 Feature #2387

#2633 Feature 2633

#2602 Feature #2602

#811 Feature 811

#1289 Feature #1289

#2336 Feature 2336

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#100 Feature 100

#319 Feature #319

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#2394 Feature 2394

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#1869 Feature #1869

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#2650 Feature #2650

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#1116 Feature #1116

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#2323 Feature 2323

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#878 Feature #878

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#2932 Feature #2932

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#1126 Feature 1126

#2267 Feature #2267

#1003 Feature 1003

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#1543 Feature #1543

#2753 Feature #2753

#1512 Feature #1512

#166 Feature 166

#823 Feature #823

#1016 Feature #1016

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#2175 Feature 2175

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#1868 Feature 1868

#2345 Feature #2345

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#2349 Feature 2349

#2832 Feature #2832

#682 Feature 682

#103 Feature 103

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#475 Feature 475

#723 Feature 723

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#993 Feature #993

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#2837 Feature #2837

#2410 Feature #2410

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#1014 Feature 1014

#279 Feature #279

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#2677 Feature 2677

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#2198 Feature 2198

#2735 Feature 2735

#553 Feature #553

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#571 Feature 571

#1344 Feature #1344

#2423 Feature 2423

#112 Feature #112

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#2560 Feature 2560

#327 Feature 327

#2440 Feature 2440

#430 Feature #430

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#914 Feature #914

#326 Feature 326

#637 Feature #637

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#1673 Feature #1673

#2518 Feature 2518

#445 Feature 445

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#1098 Feature 1098

#727 Feature 727

#1195 Feature 1195

#3039 Feature #3039

#2318 Feature 2318

#2154 Feature 2154

#1169 Feature #1169

#1353 Feature 1353

#2118 Feature #2118

#1920 Feature 1920

#3005 Feature #3005

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#2374 Feature 2374

#2300 Feature 2300

#1949 Feature 1949

#1065 Feature #1065

#860 Feature #860

#1518 Feature #1518

#3014 Feature #3014

#2757 Feature #2757

#3063 Feature 3063

#1643 Feature 1643

#1991 Feature 1991

#2072 Feature #2072

#2191 Feature 2191

#838 Feature #838

#731 Feature #731

#748 Feature #748

#1696 Feature #1696

#2030 Feature 2030

#2419 Feature #2419

#2248 Feature #2248

#122 Feature #122

#1460 Feature 1460

#1156 Feature #1156

#2544 Feature 2544

#2284 Feature #2284

#243 Feature #243

#1748 Feature #1748

#2459 Feature #2459

#2466 Feature 2466

#2113 Feature #2113

#3035 Feature #3035

#137 Feature 137

#1588 Feature #1588

#641 Feature 641

#1924 Feature #1924

#2362 Feature #2362

#770 Feature #770

#2270 Feature #2270

#486 Feature #486

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#2501 Feature 2501

#1886 Feature 1886

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#2692 Feature #2692

#1280 Feature 1280

#2565 Feature 2565

#2141 Feature 2141

#2676 Feature #2676

#1956 Feature 1956

#873 Feature #873

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#2548 Feature 2548

#937 Feature #937

#1921 Feature #1921

#2298 Feature #2298

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#545 Feature 545

#2515 Feature 2515

#1613 Feature #1613

#1984 Feature #1984

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#1533 Feature #1533

#1112 Feature #1112

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#2996 Feature #2996

#800 Feature 800

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#1423 Feature #1423

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#433 Feature 433

#2491 Feature #2491

#1581 Feature #1581

#315 Feature #315

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#2098 Feature #2098

#151 Feature 151

#2789 Feature #2789

#2528 Feature #2528

#611 Feature 611

#2406 Feature #2406

#984 Feature #984

#1656 Feature 1656

#1273 Feature #1273

#595 Feature #595

#3022 Feature #3022

#1164 Feature #1164

#666 Feature #666

#1212 Feature 1212

#158 Feature 158

#2010 Feature #2010

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#1352 Feature 1352

#1059 Feature #1059

#2665 Feature #2665

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#1012 Feature #1012

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#1617 Feature #1617

#2286 Feature 2286

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#42 Feature #42

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#2168 Feature #2168

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#2613 Feature #2613

#317 Feature #317

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#1373 Feature #1373

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Document Content

Carbon quantum dots encapsulated in super small platinum nanocrystals core-shell architecture/nitrogen doped graphene hybrid nanocomposite for electrochemical biosensing of DNA damage biomarker-8-hydroxy-2'-deoxyguanosine.
In this work, carbon quantum dots (CQD) encapsulated in super small platinum nanocrystals core-shell architecture/nitrogen doped graphene hybrid nanocomposite (CQD@PDA@PtNCs-NGR) was design synthesized. Without using any capping reagent, stabilizer and surfactant, very small CQD was served as template and anchoring point for the synthesis of Pt NCs with a super small size (2.25 nm) and a uniform distribution. Meanwhile, dopamine (DA) was used as bridging agent, positioning agent and weak reducing agent to make Pt2+ grow on the CQD. Combine the high dispersed Pt NCs with high specific surface area and high conductivity of NGR, the CQD@PDA@PtNCs-NGR shows excellent electrocatalytic performance towards the biosensing of DNA damage biomarker- 8-Hydroxy-2'-deoxyguanosine (8-OH-dG). A very low detection limit of 0.45 nM and 0.85 nM (S/N = 3), a wide linear range of 0.013 μM-109.78 μM and a high sensitivity of 7.912 μA μM-1cm-2 and 4.190 μA μM-1cm-2 were obtained. The fabricated CQD@PDA@PtNCs-NGR realized the detection of 8-OH-dG in human urine practical sample. Furthermore, CQD@PDA@PtNCs-NGR was applied for the determination of 8-OH-dG generated from damaged DNA and damaged guanine (G), respectively. This work effectively combines the electrochemical signal of 8-OH-dG with DNA damage, confirms the mechanism of DNA damage, which might pave a new way to establish the associations between degree of DNA damage and 8-OH-dG.

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