Analyzer · Sparsifire

Analyze how specific documents activate the features of the SAE. Select a dataset, a run and a document to begin.

Dataset

SAE Model

Document

Active Features

1441

MIN ACTIVATION

0.0

Details List

#3007 Feature #3007

#738 Feature 738

#1946 Feature #1946

#997 Feature 997

#579 Feature #579

#144 Feature #144

#317 Feature #317

#1255 Feature #1255

#2234 Feature 2234

#658 Feature 658

#2255 Feature #2255

#1114 Feature #1114

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#2759 Feature 2759

#2582 Feature #2582

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#1535 Feature #1535

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#452 Feature #452

#1565 Feature #1565

#1615 Feature 1615

#1099 Feature 1099

#1719 Feature 1719

#2792 Feature #2792

#2802 Feature 2802

#1920 Feature 1920

#374 Medical Imaging and Oncology

#1792 Metastatic Cancer

#2055 Feature 2055

#708 Drug Resistance Mechanisms in Cancer

#1481 Feature #1481

#2803 Feature #2803

#2845 Feature #2845

#2340 Feature 2340

#2419 Feature 2419

#2811 Feature 2811

#296 Feature 296

#2598 Feature #2598

#231 Feature 231

#1451 Feature 1451

#2133 Feature #2133

#525 Feature #525

#897 Feature #897

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#627 Feature #627

#2800 Feature 2800

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#372 Feature 372

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#824 Feature 824

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#2973 Feature #2973

#1002 Feature #1002

#50 Feature #50

#757 Feature 757

#1161 Feature 1161

#816 Feature 816

#2807 Feature #2807

#2588 Feature 2588

#902 Feature #902

#542 Feature #542

#133 Feature 133

#2291 Feature #2291

#218 Feature #218

#990 Feature 990

#941 Feature #941

#1348 Feature #1348

#2786 Feature #2786

#695 Feature #695

#2790 Feature #2790

#2138 Feature #2138

#2199 Feature #2199

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#511 Feature 511

#1905 Feature #1905

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#1985 Feature 1985

#389 Feature 389

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#2931 Feature #2931

#771 Feature #771

#2540 Feature #2540

#370 Feature 370

#1336 Feature #1336

#350 Feature #350

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#690 Feature 690

#495 Feature 495

#436 Feature 436

#1623 Feature #1623

#1972 Feature 1972

#273 Feature #273

#2963 Feature #2963

#766 Feature #766

#2797 Feature 2797

#237 Feature 237

#1944 Feature 1944

#2583 Feature 2583

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#1539 Feature #1539

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#1923 Feature 1923

#1130 Feature 1130

#2150 Feature #2150

#1984 Feature 1984

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#1929 Feature 1929

#1004 Feature #1004

#2213 Feature 2213

#406 Feature 406

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#205 Feature 205

#2436 Feature #2436

#1222 Feature #1222

#503 Feature 503

#1340 Feature 1340

#1926 Feature 1926

#2664 Feature 2664

#2934 Feature 2934

#1805 Feature 1805

#158 Feature 158

#2911 Feature 2911

#885 Feature #885

#2737 Feature 2737

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#2079 Feature 2079

#1012 Feature 1012

#2517 Feature #2517

#2125 Feature 2125

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#1870 Feature #1870

#1184 Feature 1184

#876 Feature #876

#2097 Feature 2097

#209 Feature #209

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#672 Feature 672

#1523 Feature 1523

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#1725 Feature 1725

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#1211 Feature 1211

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#2662 Feature #2662

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#1773 Feature 1773

#2900 Feature 2900

#706 Feature 706

#2887 Feature #2887

#1714 Feature #1714

#866 Feature #866

#2338 Feature 2338

#294 Feature #294

#919 Feature #919

#276 Feature #276

#435 Feature 435

#864 Feature #864

#126 Feature 126

#150 Feature 150

#1582 Feature #1582

#1632 Feature 1632

#129 Feature 129

#2043 Feature 2043

#2268 Feature #2268

#403 Feature 403

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#1196 Feature 1196

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#2160 Feature 2160

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#630 Feature 630

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#1200 Feature #1200

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#1025 Feature 1025

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#3000 Feature 3000

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#936 Feature 936

#1327 Feature 1327

#2985 Feature #2985

#1516 Feature #1516

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#191 Feature 191

#1754 Feature #1754

#1476 Feature 1476

#1233 Feature 1233

#3045 Feature 3045

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#550 Feature 550

#1312 Feature 1312

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#1132 Feature #1132

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#1198 Feature #1198

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#3022 Feature 3022

#1967 Feature #1967

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#2699 Feature 2699

#2142 Feature #2142

#1160 Feature 1160

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#1679 Feature 1679

#2916 Feature 2916

#2822 Feature #2822

#215 Feature 215

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#2253 Feature #2253

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#2578 Feature 2578

#329 Feature 329

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#323 Feature #323

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#3060 Feature #3060

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#2736 Feature #2736

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#1431 Feature #1431

#413 Feature 413

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#2368 Feature #2368

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#1821 Feature #1821

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#2421 Feature #2421

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#230 Feature #230

#1425 Feature 1425

#916 Feature #916

#176 Feature #176

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#2361 Feature 2361

#801 Feature 801

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#3068 Feature #3068

#1331 Feature 1331

#2455 Feature #2455

#1913 Feature 1913

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#305 Feature #305

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#2402 Feature #2402

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#2354 Feature #2354

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#2871 Feature #2871

#1322 Feature 1322

#444 Feature 444

#2116 Feature #2116

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#2039 Feature 2039

#1643 Feature 1643

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#2366 Feature 2366

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#1854 Feature 1854

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#1804 Feature 1804

#2339 Feature #2339

#2465 Feature 2465

#515 Feature #515

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#573 Feature 573

#1358 Feature 1358

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#1956 Feature 1956

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#718 Feature 718

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#2250 Feature 2250

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#1796 Feature #1796

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#2913 Feature 2913

#2323 Feature 2323

#1627 Feature 1627

#2572 Feature 2572

#2917 Feature 2917

#2609 Feature #2609

#2475 Feature 2475

#1540 Feature #1540

#2651 Feature #2651

#1441 Feature 1441

#2510 Feature 2510

#1758 Feature 1758

#1169 Feature 1169

#2632 Feature 2632

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#302 Feature 302

#2627 Feature #2627

#1735 Feature 1735

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#2521 Feature 2521

#1724 Feature 1724

#1306 Feature #1306

#2561 Feature #2561

#2781 Feature 2781

#2113 Feature 2113

#746 Feature 746

#1670 Feature 1670

#1364 Feature #1364

#1925 Feature 1925

#322 Feature 322

#1354 Feature 1354

#14 Feature #14

#1377 Feature #1377

#1173 Feature #1173

#518 Feature 518

#2575 Feature 2575

#2826 Feature 2826

#1087 Feature 1087

#2004 Feature 2004

#211 Feature 211

#528 Feature 528

#1355 Feature 1355

#2140 Feature 2140

#1744 Feature 1744

#2875 Feature 2875

#201 Feature 201

#234 Feature #234

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#2542 Feature #2542

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#2721 Feature 2721

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#3010 Feature 3010

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#838 Feature #838

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#1610 Feature #1610

#337 Feature 337

#1163 Feature 1163

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#401 Feature 401

#2155 Feature #2155

#861 Feature 861

#2090 Feature #2090

#2379 Feature 2379

#2563 Feature 2563

#2441 Feature 2441

#2232 Medical Case Reports & Cancer Research

#1286 Feature 1286

#707 Feature 707

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#1324 Feature 1324

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#1802 Feature #1802

#1121 Feature #1121

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#433 Feature 433

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#740 Feature #740

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#1071 Feature #1071

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#2554 Feature 2554

#2172 Feature 2172

#1556 Feature #1556

#1919 Feature 1919

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#1323 Feature #1323

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#2539 Feature 2539

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#1916 Feature #1916

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#2334 Feature 2334

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#2793 Feature #2793

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#971 Feature #971

#2742 Feature 2742

#688 Feature #688

#2843 Feature #2843

#2386 Feature 2386

#1113 Feature 1113

#2972 Sensory-Motor Integration

#210 Feature 210

#1547 Feature 1547

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#1204 Feature #1204

#1538 Feature 1538

#1361 Feature 1361

#382 Feature #382

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#1210 Feature 1210

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#2367 Feature #2367

#1205 Feature 1205

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#2844 Feature #2844

#2688 Feature #2688

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#1830 Feature #1830

#61 Feature #61

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#663 Feature #663

#2373 Feature 2373

#2161 Medical/Scientific Discourse with Ethical/Social Implications

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#2761 Feature #2761

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#208 Feature #208

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#1603 Feature 1603

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#2010 Feature 2010

#2153 Feature #2153

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#2117 Feature 2117

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#2700 Feature #2700

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#1517 Feature 1517

#1826 Feature 1826

#2858 Feature 2858

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Document Content

HPV status predicts for improved survival following chemotherapy in metastatic squamous cell carcinoma of the oropharynx.
We sought to further define prognostic and predictive value of human papillomavirus (HPV) status in metastatic squamous cell carcinoma of the oropharynx (OPC). A Surveillance, Epidemiology, and End Results custom database identified 5940 adult patients, >18-years-old, with primary SCCHN and known HPV status, diagnosed from 2013 to 2014. Wilcoxon rank-sum and Mantel-Haenszel χ2 tests compared distributions of continuous and categorical covariates. Fine-Gray competing risks regressions estimated hazard ratios by HPV status, and predictive analyses were performed including the interaction term HPV status × Receipt of Chemotherapy. 182 of 5940 patients (4.0%) had metastatic OPC at diagnosis (106/3925 [2.7%] HPV+ and 76/1894 [4.0%] HPV-). HPV+ disease was prognostic for improved 20-month cancer-specific mortality (CSM) (47.1% vs 72.5%, HR 0.43, 95% CI 0.26-0.74, p = 0.002) on univariable analysis. HPV status was predictive of response to chemotherapy-adjusted HRs for receipt of chemotherapy were 0.11 (95% CI 0.03-0.37) and 0.34 (95% CI 0.18-0.64) for HPV+ versus HPV- disease, respectively (PHPV status∗Chemotherapy = 0.036). HPV status has known prognostic value in locally advanced OPC, but data on metastatic OPC are sparse. In this work, we demonstrate that HPV status is strongly prognostic for CSM in metastatic OPC and show for the first time that HPV status predicts for response to chemotherapy.

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